منابع مشابه
Estrous cycle regulation of extrasynaptic δ-containing GABA(A) receptor-mediated tonic inhibition and limbic epileptogenesis.
The ovarian cycle affects susceptibility to behavioral and neurologic conditions. The molecular mechanisms underlying these changes are poorly understood. Deficits in cyclical fluctuations in steroid hormones and receptor plasticity play a central role in physiologic and pathophysiologic menstrual conditions. It has been suggested that synaptic GABA(A) receptors mediate phasic inhibition in the...
متن کاملMatrix metalloproteinases and epileptogenesis
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
متن کاملCNS Inflammation and Epileptogenesis
An association between acute CNS infections and seizures is reported in the literature. The etiology of these seizures is, in some cases, precipitated by epileptogenic pathogenesis of the infectious agent in the brain parenchyma. A different etiology of seizures as a consequence of infections, independent of the infectious agent, relates to the inflammatory reaction. Thirdly, the febrile respon...
متن کاملCalcific neurocysticercosis and epileptogenesis.
Neurocysticercosis is responsible for increased rates of seizures and epilepsy in endemic regions. The most common form of the disease, chronic calcific neurocysticercosis, is the end result of the host's inflammatory response to the larval cysticercus of Taenia solium. There is increasing evidence indicating that calcific cysticercosis is not clinically inactive but a cause of seizures or foca...
متن کاملSeizures, Epileptogenesis, and Epilepsy
ber of diverse variables. Some of these factors, such as genes that influence seizure susceptibility, are internal. Others, which alter normal brain excitability, such as traumatic brain injury, are external. As described elsewhere in this volume, these variables can AQ? Specific cross-ref to chapter number? have different and distinct effects. For example, genes may influence both the developm...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 1997
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.1528-1157.1997.tb01728.x